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基于血型测定的嵌合体诊断

[Diagnosis of chimerism based on blood group determination].

作者信息

Seyfriedowa H, Kuśnierz G, Górska B, Fedyk T

出版信息

Acta Haematol Pol. 1975 Apr-Jun;6(2):105-12.

PMID:1154987
Abstract

The authors report the results of blood group determinations in a 9-year-old girl in whom two populations of erythrocytes were discovered. The larger population accounting for nearly 80% of erythrocytes contained the antigen A2, the smaller population had the B antigen. Besides that differences were observed in the antigens of Duffy and Lewis systems. In the saliva A and H antigens were revealed. Familial investigations indicated the participation of two gametes of maternal origin (mother--AB, father--O) although no evidence of twin pregnancy was available. The cause of this chimaerism has not been explained.

摘要

作者报告了一名9岁女孩血型测定的结果,该女孩体内发现了两种红细胞群体。占红细胞近80%的较大群体含有A2抗原,较小群体含有B抗原。此外,还观察到达菲和刘易斯系统抗原存在差异。在唾液中发现了A和H抗原。家族调查表明有两个母系来源的配子参与其中(母亲为AB型,父亲为O型),尽管没有双胎妊娠的证据。这种嵌合体的病因尚未得到解释。

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