Stålhammar D
Acta Neurol Scand. 1975 Jul;52(1):27-37. doi: 10.1111/j.1600-0404.1975.tb02825.x.
The significance of the intracranial acceleration pressure pattern at impact to the intact skull in production of brain damage is discussed, particularly as regards the contre-coup pressures. A rigid fluid-filled cylinder was connected to the skull cavity of rabbits; the cylinder was impacted and the intracranial contents acted as a contre-coup end. The pressure pattern was also modified by injection of small quantified air volumes. The pathophysiological effects of "experimental brain concussion" with vasomotor and respiratory disturbances which occurred were related to the contre-coup pressures produced, particularly the magnitude of subatmospheric pressures and the duration of late positive pressures. Some implications on their significance for brain tissue flow are discussed.
讨论了撞击完整颅骨时颅内加速压力模式在脑损伤产生中的意义,特别是关于对冲压力。将一个刚性的充液圆柱体连接到兔子的颅腔;对圆柱体进行撞击,颅内内容物充当对冲端。通过注入少量空气也改变了压力模式。所发生的伴有血管舒缩和呼吸紊乱的“实验性脑震荡”的病理生理效应与所产生的对冲压力有关,特别是低于大气压的压力大小和晚期正压的持续时间。讨论了它们对脑组织血流意义的一些影响。