Gurney J G, van Wijngaarden E
Division of Epidemiology/Clinical Research, Department of Pediatrics, School of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Neuro Oncol. 1999 Jul;1(3):212-20. doi: 10.1093/neuonc/1.3.212.
Epidemiologic and experimental research on the potential carcinogenic effects of extremely low frequency electromagnetic fields (EMF) has now been conducted for over two decades. Cancer epidemiology studies in relation to EMF have focused primarily on brain cancer and leukemia, both from residential sources of exposure in children and adults and from occupational exposure in adult men. Because genotoxic effects of EMF have not been shown, most recent laboratory research has attempted to show biological effects that could be related to cancer promotion. In this report, we briefly review residential and occupational EMF studies on brain cancer. We also provide a general review of experimental studies as they relate both to the biological plausibility of an EMF-brain cancer relation and to the insufficiency of such research to help guide exposure assessment in epidemiologic studies. We conclude from our review that no recent research, either epidemiologic or experimental, has emerged to provide reasonable support for a causal role of EMF on brain cancer.
关于极低频电磁场（EMF）潜在致癌作用的流行病学和实验研究已经进行了二十多年。与EMF相关的癌症流行病学研究主要集中在脑癌和白血病上，这些研究涉及儿童和成人因居住环境暴露以及成年男性因职业暴露而接触EMF的情况。由于尚未发现EMF具有遗传毒性作用，最近的大多数实验室研究试图证明可能与癌症促进相关的生物学效应。在本报告中，我们简要回顾了关于脑癌的居住和职业EMF研究。我们还对实验研究进行了全面综述，这些研究既涉及EMF与脑癌关系的生物学合理性，也涉及此类研究在帮助指导流行病学研究中的暴露评估方面的不足。我们从综述中得出结论，最近无论是流行病学研究还是实验研究，都没有出现能为EMF在脑癌中起因果作用提供合理支持的证据。
