Repin V S
Patol Fiziol Eksp Ter. 2001 Apr-Jun(2):3-8.
A short history of embryonic stem cell (ESC) discovery, cell line isolation, phenotyping and cell behavior both in situ and in vitro is outlined. The path of ESC differentiation into restricted specialized cell types mediated by signal network in culture and by grafting cell into recipient tissues is considered. Potentialities of ESC as the generator of spare parts of organs for regenerative medicine and related bioethical issues are briefly outlined.
本文概述了胚胎干细胞（ESC）发现、细胞系分离、表型分析以及其在体内和体外细胞行为的简短历史。探讨了在培养中通过信号网络以及将细胞移植到受体组织中，ESC分化为受限的特定细胞类型的途径。简要概述了ESC作为再生医学器官备用部件来源的潜力以及相关的生物伦理问题。
