Chen Linjun, Li Hongxia
Life Science College of Nanjing Normal University, Nanjing, Jiangsu 210097, China.
Zhonghua Nan Ke Xue. 2004 Jan;10(1):55-8.
Human embryonic stem cells can be induced to differentiate into all kinds of cells in vitro to be applied to clinical medicine and scientific research. Because they have to be isolated from human embryos, any attempt to establish human stem cell line is prohibited by religion and ethics in some areas and countries. Parthogenetic embryonic stem cells have similar capacity of totipotency and proliferation, and can be established from parthenogenetic activation of discarded oocytes. This paper reviews the progress in the studies of the establishment of parthenogenetic embryonic stem cell line and its differentiation capacities.