Jonsson O, Lundgren Y, Wennergren G
Acta Physiol Scand. 1975 Apr;93(4):548-52. doi: 10.1111/j.1748-1716.1975.tb05847.x.
The contents of exchangeable sodium, bound sodium and total water and the extracellular space of thoracic aortas from normotensive and spontaneously hypertensive rats were measured. The aortas from the hypertensive rats contained more sodium than those from the normotensive animals while the total water content and extracellular space in the two groups were the same. The capacity to bind sodium in an osmotically inactive form was greater in the aortas from the hypertensives than in those from the normotensives. The difference in binding capacity was of the same order of magnitude as the difference in sodium content, indicating that the excess sodium in the thoracic aortas from the hypertensive rats was osmotically inactive and thus unable to cause water logging.
对正常血压大鼠和自发性高血压大鼠胸主动脉中可交换钠、结合钠、总水量及细胞外间隙的含量进行了测定。高血压大鼠的主动脉所含钠比正常血压动物的主动脉多，而两组的总含水量和细胞外间隙相同。高血压大鼠主动脉中以渗透惰性形式结合钠的能力比正常血压大鼠的主动脉更强。结合能力的差异与钠含量的差异处于同一数量级，这表明高血压大鼠胸主动脉中多余的钠是渗透惰性的，因此不会导致积水。
