Daskalogiannakis J, Ross R B, Tompson B D
Division of Orthodontics, Department of Dentistry, The Hospital for Sick Children, Toronto, Ontario, Canada.
Am J Orthod Dentofacial Orthop. 2001 Sep;120(3):280-5. doi: 10.1067/mod.2001.115038.
The purpose of this retrospective longitudinal cephalometric study was to investigate differences in craniofacial and especially mandibular morphology between patients with Pierre Robin sequence and isolated cleft palates. The experimental group comprised 96 patients (54 males and 42 females) with a history of Pierre Robin sequence. This group was compared cephalometrically with a control group of 50 patients (25 males and 25 females) with a history of isolated clefting of the palate. All 96 patients in the PR group had a lateral cephalogram at a mean age of 5.5 years. Thirty-eight of those patients had additional cephalograms at the mean ages of 10.3 years and 16.8 years. All patients in the cleft palate group had 3 corresponding cephalograms at the following mean ages: 5.7 years, 10.6 years, and 17.0 years. Twenty-nine cephalometric measurements were performed on each cephalogram with the use of computerized cephalometric software. Significant differences were identified between the 2 groups, particularly in the size and sagittal position of the mandible, which was consistently shorter in the Pierre Robin group at all 3 ages. Less severe differences were noted in the inclination of the palatal plane, the facial height proportions, and the midface depth. We conclude that patients with Pierre Robin sequence have a significantly smaller mandible as compared with patients with isolated cleft palate, and the difference does not change after the age of 5 years.
这项回顾性纵向头影测量研究的目的是调查皮埃尔·罗宾序列征患者与单纯腭裂患者在颅面尤其是下颌形态上的差异。实验组包括96例有皮埃尔·罗宾序列征病史的患者（54例男性和42例女性）。该组与50例有单纯腭裂病史的对照组患者（25例男性和25例女性）进行了头影测量比较。PR组的所有96例患者在平均年龄5.5岁时拍摄了一张侧位头影图。其中38例患者在平均年龄10.3岁和16.8岁时又拍摄了头影图。腭裂组的所有患者在以下平均年龄有3张相应的头影图：5.7岁、10.6岁和17.0岁。使用计算机化头影测量软件对每张头影图进行了29项头影测量。两组之间存在显著差异，尤其是在下颌骨的大小和矢状位置方面，皮埃尔·罗宾组在所有3个年龄时下颌骨始终较短。在腭平面倾斜度、面部高度比例和中面部深度方面差异较小。我们得出结论，与单纯腭裂患者相比，皮埃尔·罗宾序列征患者的下颌骨明显较小，且5岁以后这种差异没有变化。
