[镧离子对人红细胞形态、聚集及融合的影响]

[Effect of La2+ on the form, aggregation, and fusion of human erythrocytes].

作者信息

Sheremet'ev Iu A, Suslov F Iu, Sheremet'eva A V

机构信息

Agricultural State Academy, Nizhny Novgorod.

出版信息

Tsitologiia. 2001;43(7):648-51.

Abstract

By optical microscopy, it has been shown that the addition of La3+ ions induced transformation in the shape of erythrocytes, their aggregation and fusion. After addition of La3+ erythrocytes transform into stomatocytes. It was found that the red cell shape recovered to discoid after addition of EDTA. Neither transformation of shape nor aggregation or fusion of erythrocytes could be detected after their treatment with glutaraldehyde. A possible mechanism and significance of the shape transformation in aggregation of erythrocytes is discussed.

摘要

通过光学显微镜观察发现，添加La3+离子会导致红细胞形态发生转变、聚集和融合。添加La3+后，红细胞会转变为口形细胞。研究发现，添加乙二胺四乙酸（EDTA）后，红细胞形态会恢复为盘状。用戊二醛处理红细胞后，未检测到其形态转变、聚集或融合现象。文中讨论了红细胞聚集过程中形态转变的可能机制及意义。

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