牛在实验性和自然暴露于活布鲁氏菌流产株后的时间性细胞介导免疫反应。
Temporal cell-mediated immune responses of cattle following experimental and natural exposure to living Brucella abortus.
作者信息
Kaneene J M, Angus R D, Johnson D W, Muscoplat C C, Anderson R K, Pietz D E
出版信息
Can J Comp Med. 1979 Apr;43(2):132-41.
A study on cell-mediated immune responses in cattle with different exposure experiences to Brucella abortus was conducted by an in vitro lymphocyte stimulation assay. The purpose of this study was to determine how soon the cell-mediated immune responses would be detected following experimental exposure to B. abortus and to study the cell-mediated immune trend following experimental and natural exposure of cattle to B. abortus. The first positive cell-mediated immune responses occurred one to two weeks after experimental inoculation with living B. abortus strain 2308. The cell-mediated immune responses in these animals appeared at least one week before the appearance of of B. abortus serum agglutinating antibodies. Animals which were naturally infected with B. abortus biotypes 1 and 2 demonstrated positive cell-mediated immune responses throughout the study.
通过体外淋巴细胞刺激试验，对不同布氏杆菌流产菌暴露经历的牛的细胞介导免疫反应进行了一项研究。本研究的目的是确定在实验性暴露于布氏杆菌流产菌后多久能检测到细胞介导免疫反应，并研究牛在实验性和自然暴露于布氏杆菌流产菌后的细胞介导免疫趋势。首次阳性细胞介导免疫反应在实验接种活布氏杆菌流产菌2308株后1至2周出现。这些动物的细胞介导免疫反应至少在布氏杆菌流产菌血清凝集抗体出现前一周出现。在整个研究过程中，自然感染布氏杆菌生物型1和2的动物表现出阳性细胞介导免疫反应。
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