Roberts A P, Cheah G, Ready D, Pratten J, Wilson M, Mullany P
Department of Microbiology, Eastman Dental Institute for Oral Health Care Sciences, University College London, 256 Gray's Inn Road, London WC1X 8LD, United Kingdom.
Antimicrob Agents Chemother. 2001 Oct;45(10):2943-6. doi: 10.1128/AAC.45.10.2943-2946.2001.
Microcosm dental plaques were grown from an inoculum of human saliva in a constant-depth film fermentor. The inoculum contained four tetracycline-resistant streptococcal species, each of which contained a Tn916-like element. This element was shown to transfer to other streptococci both in filter-mating experiments and within the biofilms in the fermentor.
在恒深膜发酵罐中,以人唾液接种物培养微观世界牙菌斑。该接种物包含四种耐四环素的链球菌属菌种,每种菌种都含有一个类Tn916元件。在滤膜杂交实验以及发酵罐生物膜内,该元件均能转移至其他链球菌。