韦荣球菌属作为口腔中可转移四环素耐药性储存库的潜在作用。
Potential role of Veillonella spp. as a reservoir of transferable tetracycline resistance in the oral cavity.
作者信息
Ready D, Pratten J, Roberts A P, Bedi R, Mullany P, Wilson M
机构信息
Microbiology, Eastman Dental Hospital, UCLH NHS Foundation Trust, London WC1X 8LD, UK.
出版信息
Antimicrob Agents Chemother. 2006 Aug;50(8):2866-8. doi: 10.1128/AAC.00217-06.
Abstract
Twelve out of 96 Veillonella spp. isolated from oral samples harbored tetracycline resistance genes. The most common resistance gene was tet(M). A tet(M)-positive Veillonella dispar strain was shown to transfer a Tn916-like element to four Streptococcus spp. by conjugation at a frequency of 5.2 x 10(-6) to 4.5 x 10(-5) per recipient.
摘要
从口腔样本中分离出的96株韦荣氏菌属细菌中，有12株携带四环素抗性基因。最常见的抗性基因是tet(M)。一株tet(M)阳性的殊异韦荣氏菌菌株通过接合作用，以每受体5.2×10⁻⁶至4.5×10⁻⁵的频率将一个Tn916样元件转移至4种链球菌属细菌。
相似文献
1
Potential role of Veillonella spp. as a reservoir of transferable tetracycline resistance in the oral cavity.
Antimicrob Agents Chemother. 2006 Aug;50(8):2866-8. doi: 10.1128/AAC.00217-06.
2
The maintenance in the oral cavity of children of tetracycline-resistant bacteria and the genes encoding such resistance.
J Antimicrob Chemother. 2005 Sep;56(3):524-31. doi: 10.1093/jac/dki259. Epub 2005 Jul 18.
3
Incidence and behaviour of Tn916-like elements within tetracycline-resistant bacteria isolated from root canals.
Oral Microbiol Immunol. 2006 Aug;21(4):218-22. doi: 10.1111/j.1399-302X.2006.00279.x.
4
Transfer of antibiotic resistance by transformation with eDNA within oral biofilms.
FEMS Immunol Med Microbiol. 2010 Aug;59(3):345-9. doi: 10.1111/j.1574-695X.2010.00661.x. Epub 2010 Feb 17.
5
New Tn916-related elements causing erm(B)-mediated erythromycin resistance in tetracycline-susceptible pneumococci.
J Antimicrob Chemother. 2007 Jul;60(1):127-31. doi: 10.1093/jac/dkm120. Epub 2007 May 5.
6
Conjugal mobilization of the mega element carrying mef(E) from Streptococcus salivarius to Streptococcus pneumoniae.
FEMS Microbiol Lett. 2009 Jan;290(1):79-84. doi: 10.1111/j.1574-6968.2008.01408.x. Epub 2008 Nov 14.
7
New variants of the tet(M) gene in Clostridium difficile clinical isolates harbouring Tn916-like elements.
J Antimicrob Chemother. 2006 Jun;57(6):1205-9. doi: 10.1093/jac/dkl105. Epub 2006 Mar 24.
8
Diversity of the tetracycline resistance gene tet(M) and identification of Tn916- and Tn5801-like (Tn6014) transposons in Staphylococcus aureus from humans and animals.
J Antimicrob Chemother. 2009 Sep;64(3):490-500. doi: 10.1093/jac/dkp214. Epub 2009 Jun 16.
9
Survey of molecular determinants in Gram-positive cocci isolated from hospital settings in Argentina.
J Infect Dev Ctries. 2007 Dec 1;1(3):275-83.
10
Assessment of antimicrobial resistance transfer between lactic acid bacteria and potential foodborne pathogens using in vitro methods and mating in a food matrix.
Foodborne Pathog Dis. 2009 Oct;6(8):925-33. doi: 10.1089/fpd.2009.0278.
引用本文的文献
1
Polymicrobial Biofilms: Interkingdom Interactions, Resistance and Therapeutic Strategies.
Microb Biotechnol. 2025 Aug;18(8):e70218. doi: 10.1111/1751-7915.70218.
2
The Distribution of Eight Antimicrobial Resistance Genes in , , and Strains Isolated from Dental Plaque as Oral Commensals.
Trop Med Infect Dis. 2023 Nov 16;8(11):499. doi: 10.3390/tropicalmed8110499.
3
Polymicrobial Infections and Biofilms: Clinical Significance and Eradication Strategies.
Antibiotics (Basel). 2022 Dec 1;11(12):1731. doi: 10.3390/antibiotics11121731.
4
Inverse PCR-based detection reveal novel mobile genetic elements and their associated genes in the human oral metagenome.
BMC Oral Health. 2022 May 27;22(1):210. doi: 10.1186/s12903-022-02209-y.
5
16S rDNA analysis of the intestinal microbes in osteoporotic rats.
Biosci Microbiota Food Health. 2021;40(3):156-167. doi: 10.12938/bmfh.2020-065. Epub 2021 Feb 23.
6
Microbiological and host-derived biomarker evaluation following non-surgical periodontal therapy with short-term administration of systemic antimicrobials: secondary outcomes of an RCT.
Sci Rep. 2020 Oct 1;10(1):16322. doi: 10.1038/s41598-020-73054-8.
7
Clinical Detection of Chronic Rhinosinusitis through Next-Generation Sequencing of the Oral Microbiota.
Microorganisms. 2020 Jun 26;8(6):959. doi: 10.3390/microorganisms8060959.
8
"It Takes a Village": Mechanisms Underlying Antimicrobial Recalcitrance of Polymicrobial Biofilms.
J Bacteriol. 2019 Dec 6;202(1). doi: 10.1128/JB.00530-19.
9
Relationship between tetracycline antibiotic susceptibility and genotype in oral cavity clinical isolates.
Antimicrob Resist Infect Control. 2019 Feb 4;8:27. doi: 10.1186/s13756-019-0483-9. eCollection 2019.
10
Opportunistic bacteria confer the ability to ferment prebiotic starch in the adult cystic fibrosis gut.
Gut Microbes. 2019;10(3):367-381. doi: 10.1080/19490976.2018.1534512. Epub 2018 Oct 25.
本文引用的文献
1
Update on acquired tetracycline resistance genes.
FEMS Microbiol Lett. 2005 Apr 15;245(2):195-203. doi: 10.1016/j.femsle.2005.02.034.
2
Prevalence, proportions, and identities of antibiotic-resistant bacteria in the oral microflora of healthy children.
Microb Drug Resist. 2003 Winter;9(4):367-72. doi: 10.1089/107662903322762806.
3
Prevalence and identification of tetracycline-resistant oral bacteria in children not receiving antibiotic therapy.
FEMS Microbiol Lett. 2003 Nov 7;228(1):99-104. doi: 10.1016/S0378-1097(03)00740-7.
4
Prevalence of tetracycline resistance genes in oral bacteria.
Antimicrob Agents Chemother. 2003 Mar;47(3):878-82. doi: 10.1128/AAC.47.3.878-882.2003.
5
Antibiotic toxicity, interactions and resistance development.
Periodontol 2000. 2002;28:280-97. doi: 10.1034/j.1600-0757.2002.280112.x.
6
Transfer of TN916-like elements in microcosm dental plaques.
Antimicrob Agents Chemother. 2001 Oct;45(10):2943-6. doi: 10.1128/AAC.45.10.2943-2946.2001.
7
Multiplex PCR for the detection of tetracycline resistant genes.
Mol Cell Probes. 2001 Aug;15(4):209-15. doi: 10.1006/mcpr.2001.0363.
8
Veillonella parvula meningitis: case report and review of Veillonella infections.
Clin Infect Dis. 2000 Sep;31(3):839-40. doi: 10.1086/314046.
9
The RDP (Ribosomal Database Project) continues.
Nucleic Acids Res. 2000 Jan 1;28(1):173-4. doi: 10.1093/nar/28.1.173.
10
The tetracyclines.
Mayo Clin Proc. 1999 Jul;74(7):727-9. doi: 10.4065/74.7.727.
Zotero 插件