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1
Accelerated uptake of 5-hydroxytryptamine by human blood platelets enriched in a sialic acid.富含唾液酸的人血小板对5-羟色胺的摄取加速。
Biochem J. 1975 May;148(2):335-6. doi: 10.1042/bj1480335.
2
Sialic acid in platelets of schizophrenic patients.
Prog Neuropsychopharmacol Biol Psychiatry. 1988;12(1):103-7. doi: 10.1016/0278-5846(88)90065-6.
3
Low serotonin uptake by platelets in leprosy and a new approach to prevent it.
Int J Lepr Other Mycobact Dis. 1981 Mar;49(1):42-8.
4
Serum albumin stimulates serotonin uptake into human blood platelets.血清白蛋白刺激血清素摄取进入人体血小板。
Life Sci. 1989;44(18):1251-8. doi: 10.1016/0024-3205(89)90361-5.
5
Decreased uptake of 5-hydroxytryptamine in blood platelets from depressed patients.抑郁症患者血小板中5-羟色胺摄取减少。
Nature. 1976 Aug 12;262(5569):596-8. doi: 10.1038/262596a0.
6
Shape change and uptake of 5-hydroxytryptamine in human blood platelets: action of neuropsychotropic drugs.5-羟色胺在人血小板中的形态变化与摄取：神经精神药物的作用
Life Sci. 1979 May 14;24(20):1833-40. doi: 10.1016/0024-3205(79)90233-9.
7
Transport of 5-hydroxytryptamine by rat and human platelets [proceedings].大鼠和人血小板对5-羟色胺的转运[会议论文集]
Br J Pharmacol. 1976 Oct;58(2):300P-301P.
8
Plasma free 5-hydroxytryptamine (5-HT): evidence of an increase induced by LM 5008, a potent 5-HT uptake inhibitor.血浆游离5-羟色胺（5-HT）：强效5-HT摄取抑制剂LM 5008诱导其升高的证据。
Life Sci. 1978 Oct 2;23(13):1317-24. doi: 10.1016/0024-3205(78)90389-2.
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Effects on platelet function of removal of platelet sialic acid by neuraminidase.神经氨酸酶去除血小板唾液酸对血小板功能的影响。
Lab Invest. 1975 Apr;32(4):476-84.
10
5-Hydroxytryptamine uptake by blood platelets of unipolar and bipolar depressed patients.
Neuropsychobiology. 1984;12(2-3):93-5. doi: 10.1159/000118116.

引用本文的文献

1
Glycosyl modification facilitates homo- and hetero-oligomerization of the serotonin transporter. A specific role for sialic acid residues.糖基修饰促进血清素转运体的同源和异源寡聚化。唾液酸残基的特定作用。
J Biol Chem. 2003 Nov 7;278(45):43991-4000. doi: 10.1074/jbc.M306360200. Epub 2003 Aug 27.
2
Increase in sialic acids removable by neuraminidase during the shape change of platelets.血小板形态改变过程中可被神经氨酸酶去除的唾液酸增加。
Biochem J. 1976 Sep 15;158(3):655-7. doi: 10.1042/bj1580655.

本文引用的文献

1
Effects of the numbers and sizes of platelet aggregates on the optical density of plasma.血小板聚集体的数量和大小对血浆光密度的影响。
Nature. 1967 Sep 2;215(5105):1027-9. doi: 10.1038/2151027a0.
2
5-Hydroxytryptamine uptake and release in relation to aggregation of rabbit platelets.5-羟色胺摄取与释放与兔血小板聚集的关系
J Physiol. 1969 Apr;201(2):409-23. doi: 10.1113/jphysiol.1969.sp008763.
3
The relation between the 5-hydroxytryptamine content and aggregation of rabbit platelets.兔血小板中5-羟色胺含量与聚集之间的关系。
J Physiol. 1969 Apr;201(2):397-408. doi: 10.1113/jphysiol.1969.sp008762.
4
Effects of 5-hydroxytryptamine on platelet aggregation.5-羟色胺对血小板聚集的影响。
Nature. 1968 Apr 13;218(5137):137-41. doi: 10.1038/218137a0.
5
Platelet aggregation in washed suspensions.洗涤悬浮液中的血小板聚集
Scand J Haematol. 1971;8(3):161-8. doi: 10.1111/j.1600-0609.1971.tb01967.x.
6
Relative activities on and uptake by human blood platelets of 5-hydroxytryptamine and several analogues.5-羟色胺及几种类似物对人体血小板的相对活性及摄取情况
Br J Pharmacol. 1972 Jan;44(1):117-39. doi: 10.1111/j.1476-5381.1972.tb07244.x.
7
Effect of 5-hydroxytryptamine on the potassium ion exchange of human platelets enriched in sialic acid.5-羟色胺对富含唾液酸的人血小板钾离子交换的影响。
Biochem J. 1972 Oct;129(4):977-8. doi: 10.1042/bj1290977.
8
Changes in the aggregation of platelets enriched in sialic acid.富含唾液酸的血小板聚集情况的变化。
Nat New Biol. 1972 Apr 19;236(68):213-4. doi: 10.1038/newbio236213a0.
9
Intracellular localization of liver sugar nucleotide glycoprotein glycosyltransferases in a Golgi-rich fraction.肝脏糖核苷酸糖蛋白糖基转移酶在富含高尔基体组分中的细胞内定位。
J Biol Chem. 1970 Mar 10;245(5):1090-100.
10
The sialic acids. X. Purification and properties of cytidine 5'-monophosphosialic acid synthetase.唾液酸。X. 胞苷5'-单磷酸唾液酸合成酶的纯化及性质
J Biol Chem. 1966 Dec 10;241(23):5643-50.

富含唾液酸的人血小板对5-羟色胺的摄取加速。

Accelerated uptake of 5-hydroxytryptamine by human blood platelets enriched in a sialic acid.

作者信息

Mester L, Michal F, Born G V

出版信息

Biochem J. 1975 May;148(2):335-6. doi: 10.1042/bj1480335.

DOI:10.1042/bj1480335
PMID:1156409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1165542/
Abstract

The enzymically catalysed incorporation of N-acetylneuraminic acid into human platelets, whether suspended in their own citrated plasma or in buffered saline containing 0.17 mM-sucrose, accelerated the uptake of 5-hydroxytryptamine. This acceleration decreased with time. The observations may be explained by assuming that N-acetylneuraminic acid is a component of a transport receptor for 5-hydroxytryptamine.

摘要

无论悬浮于自身的枸橼酸盐血浆中还是含有0.17 mM蔗糖的缓冲盐水中，经酶催化将N-乙酰神经氨酸掺入人血小板，均可加速5-羟色胺的摄取。这种加速作用随时间而降低。这些观察结果可通过假设N-乙酰神经氨酸是5-羟色胺转运受体的一个组分来解释。