富含唾液酸的人血小板对5-羟色胺的摄取加速。
Accelerated uptake of 5-hydroxytryptamine by human blood platelets enriched in a sialic acid.
作者信息
Mester L, Michal F, Born G V
出版信息
Biochem J. 1975 May;148(2):335-6. doi: 10.1042/bj1480335.
Abstract
The enzymically catalysed incorporation of N-acetylneuraminic acid into human platelets, whether suspended in their own citrated plasma or in buffered saline containing 0.17 mM-sucrose, accelerated the uptake of 5-hydroxytryptamine. This acceleration decreased with time. The observations may be explained by assuming that N-acetylneuraminic acid is a component of a transport receptor for 5-hydroxytryptamine.
摘要
无论悬浮于自身的枸橼酸盐血浆中还是含有0.17 mM蔗糖的缓冲盐水中，经酶催化将N-乙酰神经氨酸掺入人血小板，均可加速5-羟色胺的摄取。这种加速作用随时间而降低。这些观察结果可通过假设N-乙酰神经氨酸是5-羟色胺转运受体的一个组分来解释。
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