调节性T细胞与过敏性哮喘。
Regulatory T cells and allergic asthma.
作者信息
Yssel H, Lécart S, Pène J
机构信息
Inserm U454, CHU Arnaud de Villeneuve, 371 avenue Doyen Gaston Giraud, 34295 Montpellier cedex 5, France.
出版信息
Microbes Infect. 2001 Sep;3(11):899-904. doi: 10.1016/s1286-4579(01)01450-2.
Abstract
Because of the characteristic airway inflammation observed in allergic asthma, the pathogenesis of this disease may be due, in part, to a lack of anti-inflammatory and immune suppressive mechanisms. Here, we discuss the possible involvement and therapeutic use of T regulatory cells and their soluble factors in this multifactorial disease.
摘要
由于在过敏性哮喘中观察到的特征性气道炎症，这种疾病的发病机制可能部分归因于抗炎和免疫抑制机制的缺乏。在此，我们讨论了调节性T细胞及其可溶性因子在这种多因素疾病中的可能作用和治疗用途。
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