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[慢性复发性胰腺炎不同阶段患者血液中的白细胞介素-8及其在胰腺炎发病机制中的作用]

[Blood interleukin-8 in patients with different stages of chronic relapsing pancreatitis and its role in the pathogenesis of pancreatitis].

作者信息

Zhukova E N

出版信息

Ross Gastroenterol Zh. 2001(1):15-8.

Abstract

Interleukin-8 was examined in 55 patients with chronic relapsing pancreatitis in the stage of aggravation, change to remission and stable remission. The highest interleukin-8 was revealed in the patients with aggravation of pancreatitis. The author considers, that interleukin-8 is connected with high concentration of oxygen active forms in neutrophils in the patients with this stage of disease. It is concluded, that interleukin-8 takes part in the pathogenesis of relapsing pancreatitis. High levels of interleukin-8 were revealed in some patients with stable pancreatitis remission. The author thinks, that asymptomatic pancreatitis relapses may be present.

摘要

对55例慢性复发性胰腺炎患者在病情加重期、转为缓解期和稳定缓解期进行了白细胞介素-8检测。胰腺炎加重期患者的白细胞介素-8水平最高。作者认为,白细胞介素-8与该疾病阶段患者中性粒细胞中高浓度的氧活性形式有关。得出的结论是,白细胞介素-8参与了复发性胰腺炎的发病机制。在一些胰腺炎稳定缓解期的患者中也发现了高水平的白细胞介素-8。作者认为,可能存在无症状的胰腺炎复发。

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