Kaneko M, Watanabe J, Ueno E
Department of Pediatrics, Shizuoka Red Cross Hospital, Shizuoka-shi, Japan.
J Perinat Med. 2001;29(4):351-6. doi: 10.1515/JPM.2001.050.
We reported two case studies of meconium aspiration syndrome (MAS) with pulmonary hemorrhage in which we applied surfactant lavage and replacement. Surfactant lavage and replacement of MAS with pulmonary hemorrhage appears to be effective and safe adjunctive therapy. The relatively small replacement doses of surfactant required may be attributed to surfactant lavage followed by surfactant replacement. We suggest that surfactant lavage and replacement of MAS with pulmonary hemorrhage should be further investigated by a randomized controlled trial.
我们报告了两例胎粪吸入综合征（MAS）合并肺出血的病例研究，我们在其中应用了表面活性剂灌洗和替代疗法。表面活性剂灌洗和替代疗法对合并肺出血的MAS似乎是一种有效且安全的辅助治疗方法。所需表面活性剂替代剂量相对较小可能归因于先进行表面活性剂灌洗然后再进行表面活性剂替代。我们建议应通过随机对照试验对合并肺出血的MAS的表面活性剂灌洗和替代疗法进行进一步研究。
