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Changes in sensitivity to cytotoxic agents occurring during the life history of monolayer cultures of a mouse tumour cell line.
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The relationship between tumour geometry and the response of tumour cells to cytotoxic drugs--an in vitro study using EMT6 multicellular spheroids.
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The sensitivity to cytotoxic agents of the EMT6 tumor in vivo. Comparative response of lung nodules in rapid expotential growth and of the solid flank tumour.
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Comparative chemosensitivity of exponential- versus plateau-phase cells in both in vitro model systems.
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Effects of alkylating agents on the DNA replication of cultured Yoshida sarcoma cells.
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Cell proliferation kinetics and drug sensitivity of exponential and stationary populations of cultured L1210 cells.
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Preclinical studies and clinical correlation of the effect of alkylating dose.
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Evidence for reinitiation of proliferative activity following alkylation or radiation.
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Preclinical evaluation of Laromustine for use in combination with radiation therapy in the treatment of solid tumors.
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Kinetic resistance to anticancer agents.
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The clinical value of immunohistochemically demonstrable CEA in breast cancer: a possible method of selecting patients for adjuvant chemotherapy.
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Effect of cell density on intracellular adriamycin concentration and cytotoxicity in exponential and plateau phase EMT6 cells.
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Survival and cell cycle kinetics responses of Chinese hamster ovary cells, and clones of human adenocarcinoma of the stomach and astrocytoma to diaziquone (AZQ) in vitro.
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Clinical pharmacokinetics of oral CCNU (lomustine).
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The response to cytotoxic drugs of EMT6 cells treated either as intact or disaggregated spheroids.
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Enhancement of adriamycin-induced killing after delayed plating of plateau-phase V79-cells.
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Evidence for induction and repair of potentially lethal damage in plateau-phase V79 cells after exposure to adriamycin. The importance of removal of adriamycin released from the cells during the post-treatment incubation period.
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Action of cytotoxic agents on the erythroid system of the mouse.
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Comparison of the sensitivity of normal hematopoietic and transplanted lymphoma colony-forming cells to chemotherapeutic agents administered in vivo.
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Sensitivity of confluent and cycling embryonic hamster cells to sulfur mustard, 1,3-bis(2-chloroethyl)-1-nitrosourea, and actinomycin D.
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Factors determining cell killing by chemotherapeutic agents in vivo. II. Melphalan, chlorambucil and nitrogen mustard.
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Survival responses of dividing and nondividing mammalian cells after treatment with hydroxyurea, arabinosylcytosine, or adriamycin.
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Survival kinetics of cultured human lymphoma cells exposed to adriamycin.
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Plateau-phase cultures of mammalian cells: an in vitro model for human cancer.
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Cell proliferation and the action of cytotoxic agents on haemopoietic tissue.
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Tumor chemotherapy: efficacy dependent on mode of growth.
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Differential lethal effect of cytotoxic agents on proliferating and nonproliferating lymphoid cells.
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