EMT6肿瘤在体内对细胞毒性药物的敏感性。快速指数生长的肺结节和侧腹实体瘤的比较反应。
The sensitivity to cytotoxic agents of the EMT6 tumor in vivo. Comparative response of lung nodules in rapid expotential growth and of the solid flank tumour.
作者信息
Twentyman P R, Bleehen N M
出版信息
Br J Cancer. 1976 Mar;33(3):320-8. doi: 10.1038/bjc.1976.46.
Abstract
Experiments are described in which dose-response data have been obtained for EMT6 mouse tumour cells growing in vivo and exposed to various cytotoxic agents. A comparison has been made of the response of solid tumours in the flank and of rapidly growing lung nodules. The results are discussed with regard to their cell kinetic implications and compared with our results for the chemosensitivity of EMT6 cells in exponential and plateau phase growth in vitro.
摘要
本文描述了一些实验，其中获取了在体内生长并暴露于各种细胞毒性剂的EMT6小鼠肿瘤细胞的剂量反应数据。对侧腹实体瘤和快速生长的肺结节的反应进行了比较。讨论了结果的细胞动力学意义，并与我们关于EMT6细胞在体外指数期和平稳期生长时化学敏感性的结果进行了比较。
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本文引用的文献
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