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[直立不耐受综合征]

[Orthostatic intolerance syndromes].

作者信息

Gónzalez-Hermosillo J A

机构信息

Departamento de Electrocardiografía y Electrofisiología, Instituto Nacional de Cardiología Ignacio Chávez, INCICH, Juan Badiano No. 1, 14080 México, D.F.

出版信息

Arch Cardiol Mex. 2001 Jan-Mar;71 Suppl 1:S58-62.

Abstract

In patients with an orthostatic intolerance, the hemodynamic response to standing, may identify an abnormality know as postural orthostatic tachycardia syndrome or orthostatic hypotension, that can often be treated without further testing. When the response to standing is normal, tilt-table testing may be useful in making the diagnosis of vasovagal syncope or postural orthostatic tachycardia syndrome and guiding treatment. In evaluating the results of tilt-table testing, an important consideration is the distinction between vasovagal syncope, and the dysautonomic response to tilt characterized by a gradual and progressive decrease in blood pressure that leads to syncope. Current practice patterns suggest that beta blockers, fludrocortisone, and midodrine are commonly used to treat patients with vasovagal syncope. These also suggest that patients with the postural orthostatic tachycardia syndrome, and with the dysautonomic response, are better treated with fludrocortisone and midodrine.

摘要

对于体位性不耐受患者,站立时的血流动力学反应可能会识别出一种称为体位性直立性心动过速综合征或体位性低血压的异常情况,通常无需进一步检查即可进行治疗。当站立反应正常时,倾斜试验可能有助于诊断血管迷走性晕厥或体位性直立性心动过速综合征并指导治疗。在评估倾斜试验结果时,一个重要的考虑因素是区分血管迷走性晕厥以及以血压逐渐和进行性下降导致晕厥为特征的对倾斜的自主神经功能异常反应。目前的临床实践模式表明,β受体阻滞剂、氟氢可的松和米多君常用于治疗血管迷走性晕厥患者。这些模式还表明,体位性直立性心动过速综合征患者以及有自主神经功能异常反应的患者,使用氟氢可的松和米多君治疗效果更佳。

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