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单心室患者的房室瓣反流:双向腔肺吻合术的影响

Atrioventricular valve regurgitation in patients with single ventricle: impact of the bidirectional cavopulmonary anastomosis.

作者信息

Mahle W T, Cohen M S, Spray T L, Rychik J

机构信息

Division of Cardiology, The Children's Hospital of Philadelphia, Pennsylvania, USA.

出版信息

Ann Thorac Surg. 2001 Sep;72(3):831-5. doi: 10.1016/s0003-4975(01)02893-4.

Abstract

BACKGROUND

It is not known whether atrioventricular valve regurgitation (AVVR) can improve in some patients after the bidirectional cavopulmonary anastomosis (BCPA) without undertaking concomitant valvuloplasty.

METHODS

We retrospectively reviewed our experience with patients who underwent the BCPA between June 1989 and June 2000 with specific attention to those patients with moderate or severe AVVR. The degree of AVVR was determined by color Doppler echocardiography. During the study period there were 576 patients who underwent BCPA at a median age of 6.8 months (range, 1.3 months to 4.8 years). The majority of subjects (66%) had a tricuspid valve as the systemic atrioventricular valve. Significant (moderate or severe) AVVR before BCPA was noted in 36 of 576 patients (6%) and was significantly more prevalent (8 of 52 patients, 15%; p = 0.01) in patients with a common atrioventricular canal.

RESULTS

Of the 36 subjects with moderate or severe AVVR, 8 had interventions (6 valvuloplasty, 2 aortic arch dilation) at BCPA. There was 1 hospital death (2.8%). Of the remaining 27 survivors who did not undergo additional interventions at BCPA, improvement in AVVR (mild or none) was noted in 6 (22%) at intermediate follow-up (median, 2 years; range, 0.5 to 3.1 years). The presence of significant AVVR before BCPA was not significantly associated with hospital survival or intermediate-term freedom from death or transplantation.

CONCLUSIONS

We conclude that AVVR improves in some patients after BCPA and that valvuloplasty is not justified in all patients with moderate preoperative AVVR.

摘要

背景

对于某些患者,在未同时进行瓣膜成形术的双向腔肺吻合术(BCPA)后,房室瓣反流(AVVR)是否会改善尚不清楚。

方法

我们回顾性分析了1989年6月至2000年6月期间接受BCPA患者的经验,特别关注中度或重度AVVR患者。通过彩色多普勒超声心动图确定AVVR的程度。在研究期间,有576例患者接受了BCPA,中位年龄为6.8个月(范围为1.3个月至4.8岁)。大多数受试者(66%)以三尖瓣作为体循环房室瓣。576例患者中有36例(6%)在BCPA前存在显著(中度或重度)AVVR,在共同房室通道患者中更为普遍(52例中有8例,15%;p = 0.01)。

结果

36例中度或重度AVVR患者中,8例在BCPA时进行了干预(6例瓣膜成形术,2例主动脉弓扩张)。有1例医院死亡(2.8%)。其余27例在BCPA时未接受额外干预的幸存者中,6例(22%)在中期随访(中位时间2年;范围0.5至3.1年)时AVVR有所改善(轻度或无反流)。BCPA前存在显著AVVR与医院生存率或中期免于死亡或移植无显著相关性。

结论

我们得出结论,BCPA后部分患者的AVVR有所改善,并非所有术前中度AVVR患者都有必要进行瓣膜成形术。

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