Chatsantiprapa K, Chokkanapitak J, Pinpradit N
Faculty of Pharmacuetical Sciences, Khon Kaen University, Thailand.
Inj Prev. 2001 Sep;7(3):214-7. doi: 10.1136/ip.7.3.214.
To identify host and environment characteristics associated with poison exposure among preschool children in Thailand.
A matched case-control study in 20 public hospitals in Khon Kaen province.
Cases comprised 100 consecutive preschool children attending hospital between September 1997 and February 1999 because of reported exposure to a poison. Controls were three children matched by age, sex and area of residence to each case, who had never attended a hospital for this reason. Risk factors were elicited by interviewing the children's caregivers at their homes using a structured questionnaire and analyzed using conditional logistic regression.
Number of siblings, whether the child was "medicine eating" and "rushing to explore new objects", the child's activities while the caregiver was working during the daytime, the child's distance from the caregiver while the caregiver was working, whether the child was taken to a non-agricultural worksite, and the number of used containers around the residence, were all statistically significant in univariate analyses. However, when all significant variables were included in a multivariate model, only "medicine eating" and the number of used containers around the residence remained statistically significant.
Attention to "medicine eating" and used containers through increased supervision could be a protective factor against poison exposure for these children. To reduce risk, caregivers should not refer to medicines as foods and used containers should be systematically collected for disposal or recycling.
确定泰国学龄前儿童中毒暴露相关的宿主和环境特征。
在孔敬府的20家公立医院开展一项配对病例对照研究。
病例包括1997年9月至1999年2月期间因报告有中毒暴露而住院的100名连续的学龄前儿童。对照为按年龄、性别和居住地区与每个病例配对的3名儿童,他们从未因该原因住院。通过使用结构化问卷在家中对儿童的照料者进行访谈来获取危险因素,并使用条件逻辑回归进行分析。
在单因素分析中,兄弟姐妹数量、儿童是否“吃药”和“急于探索新事物”、照料者白天工作时儿童的活动、照料者工作时儿童与照料者的距离、儿童是否被带到非农业工作场所,以及住所周围用过的容器数量,均具有统计学意义。然而,当所有显著变量纳入多变量模型时,只有“吃药”和住所周围用过的容器数量仍具有统计学意义。
通过加强监管关注“吃药”行为和用过的容器,可能是预防这些儿童中毒暴露的保护因素。为降低风险,照料者不应将药品称为食物,用过的容器应系统收集以便处理或回收。