Patel L, Wales J K, Kibirige M S, Massarano A A, Couriel J M, Clayton P E
Department of Child Health, University of Manchester, Booth Hall Childrens Hospital, Manchester M9 7AA, UK.
Arch Dis Child. 2001 Oct;85(4):330-4. doi: 10.1136/adc.85.4.330.
Symptomatic adrenal insufficiency, presenting as hypoglycaemia or poor weight gain, may occur on withdrawal of corticosteroid treatment but has not previously been reported during inhaled corticosteroid treatment. This case series illustrates the occurrence of clinically significant adrenal insufficiency in asthmatic children while patients were on inhaled corticosteroid treatment and the unexpected modes of presentation. General practitioners and paediatricians need to be aware that this unusual but acute serious complication may occur in patients treated with inhaled corticosteroids.
症状性肾上腺功能不全表现为低血糖或体重增加不佳，可能在停用皮质类固醇治疗时发生，但此前尚未有在吸入性皮质类固醇治疗期间发生的报道。本病例系列阐述了哮喘儿童在接受吸入性皮质类固醇治疗时发生具有临床意义的肾上腺功能不全的情况以及意外的表现方式。全科医生和儿科医生需要意识到，接受吸入性皮质类固醇治疗的患者可能会出现这种不寻常但急性严重的并发症。
