Kawamura H, Dunbar M J, Murray P, Bourne R B, Rorabeck C H
Division of Orthopaedics, University of Western Ontario, London, Ontario, Canada.
J Bone Joint Surg Am. 2001 Sep;83(9):1333-8.
We previously reported our two and five-year results of arthroplasty with the Porous Coated Anatomic total hip prosthesis. We now report on the performance of this prosthesis at ten to fourteen years.
The results of 311 total hip replacements in which a Porous Coated Anatomic prosthesis was inserted without cement in 279 patients were analyzed prospectively. The average age of the patients at the time of the replacement was sixty--one years (range, twenty to eighty-one years). Sixty-four patients (seventy-six hips) died postoperatively. Forty-five patients (forty-seven hips) were lost to follow-up, and four were excluded because of their medical condition. One hundred and sixty-eight patients (187 hips) were followed for ten to fourteen years (average, twelve years). Seventeen of those patients (seventeen hips) had a revision.
The overall survival rate (with any revision as the end point) was 90.0% +/- 5.4% at fourteen years, with an average Harris hip score of 85 +/- 14 points. The prevalence of thigh pain was 36% (fifty-six of 157) in the late period (more than ten years postoperatively). Radiographs showed stable fixation, with bone ingrowth, of 83% (130) of the 156 acetabular components and 88% (137) of the 156 femoral components at the latest follow-up evaluation. Men had a significantly higher rate of femoral osteolysis than did women (p < 0.001). The rates of acetabular and femoral osteolysis associated with 32-mm femoral heads (49% [twenty-three] of forty-seven and 70% [thirty-three] of forty-seven, respectively) were significantly higher (p < 0.01) than those associated with 26-mm heads (26% [twenty-eight] of 109 and 30% [thirty-three] of 109, respectively). Despite this, revision (removal or exchange of components) was not directly related to head size; instead, it was related to polyethylene thickness.
There have been persistent problems with the Porous Coated Anatomic hip system, including thigh pain and an increasing prevalence of osteolysis with time. Revision because of aseptic loosening was related more to the thickness of the polyethylene liner than to the size of the femoral head. Femoral heads with a 32-mm diameter did not increase the risk for revision provided that an adequate thickness of polyethylene had been used.
我们之前报告了采用多孔涂层解剖型全髋关节假体进行关节成形术的两年和五年结果。现在我们报告该假体在10至14年时的性能。
对279例患者未使用骨水泥植入多孔涂层解剖型假体的311例全髋关节置换结果进行前瞻性分析。置换时患者的平均年龄为61岁(范围20至81岁)。64例患者(76髋)术后死亡。45例患者(47髋)失访,4例因健康状况被排除。168例患者(187髋)接受了10至14年(平均12年)的随访。其中17例患者(17髋)进行了翻修。
以任何翻修为终点,14年时的总体生存率为90.0%±5.4%,Harris髋关节平均评分为85±14分。晚期(术后10年以上)大腿疼痛的发生率为36%(157例中的56例)。在最近的随访评估中,X线片显示156个髋臼组件中有83%(130个)和156个股骨组件中有88%(137个)固定稳定且有骨长入。男性股骨骨溶解的发生率显著高于女性(p<0.001)。与32毫米股骨头相关的髋臼和股骨骨溶解发生率(分别为47例中的49%[23例]和47例中的70%[33例])显著高于与26毫米股骨头相关的发生率(分别为109例中的26%[28例]和109例中的30%[33例])(p<0.01)。尽管如此,翻修(取出或更换组件)与股骨头大小无直接关系;相反,与聚乙烯厚度有关。
多孔涂层解剖型髋关节系统一直存在问题,包括大腿疼痛和骨溶解发生率随时间增加。因无菌性松动进行的翻修更多与聚乙烯内衬的厚度有关,而非与股骨头大小有关。只要使用了足够厚度的聚乙烯,32毫米直径的股骨头不会增加翻修风险。