一名接受皮质类固醇治疗的囊性纤维化患者在感染洋葱伯克霍尔德菌败血症后的生存情况。
Survival following Burkholderia cepacia sepsis in a patient with cystic fibrosis treated with corticosteroids.
作者信息
Kazachkov M, Lager J, LiPuma J, Barker P M
机构信息
Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7220, USA.
出版信息
Pediatr Pulmonol. 2001 Oct;32(4):338-40. doi: 10.1002/ppul.1127.
We describe an 11-year-old girl with cystic fibrosis (CF) who presented with respiratory failure and Burkholderia cepacia bacteremia (cepacia syndrome). She survived her illness after aggressive treatment with parenteral antibiotics and corticosteroids. We speculate that treatment with corticosteroids may decrease the influx of proinflammatory cytokines and neutrophil-induced inflammation, with resulting improvement in the outcome of cepacia syndrome in CF patients.
我们描述了一名患有囊性纤维化（CF）的11岁女孩，她出现了呼吸衰竭和洋葱伯克霍尔德菌血症（洋葱伯克霍尔德菌综合征）。在接受肠外抗生素和皮质类固醇积极治疗后，她从疾病中存活下来。我们推测，皮质类固醇治疗可能会减少促炎细胞因子的流入和中性粒细胞诱导的炎症，从而改善CF患者洋葱伯克霍尔德菌综合征的预后。
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