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丹麦囊性纤维化患者中未发现洋葱伯克霍尔德菌医院内交叉感染的证据。

Lack of evidence of nosocomial cross-infection by Burkholderia cepacia among Danish cystic fibrosis patients.

作者信息

Ryley H C, Ojeniyi B, Høiby N, Weeks J

机构信息

Department of Medical Microbiology, University of Wales College of Medicine, Heath Park, Cardiff, UK.

出版信息

Eur J Clin Microbiol Infect Dis. 1996 Sep;15(9):755-8. doi: 10.1007/BF01691967.

DOI:10.1007/BF01691967
PMID:8922580
Abstract

Burkholderia cepacia isolates from nine of the ten Danish cystic fibrosis (CF) patients known between 1975 and the present day to carry this organism were investigated. Eight distinct genotypes were found with polymerase chain reaction ribotyping and pulsed-field gel electrophoresis. The results indicate that there is little patient-to-patient cross-infection with Burkholderia cepacia within the Danish CF population, even though the majority of patients attend the same CF clinic on a regular basis.

摘要

对1975年至目前已知感染该细菌的10名丹麦囊性纤维化(CF)患者中的9名患者所分离出的洋葱伯克霍尔德菌进行了研究。通过聚合酶链反应核糖体分型和脉冲场凝胶电泳发现了8种不同的基因型。结果表明,在丹麦CF患者群体中,即使大多数患者定期前往同一家CF诊所就诊,洋葱伯克霍尔德菌在患者之间的交叉感染也很少。

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本文引用的文献

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Comparison of genome fingerprinting with conventional typing methods used on Pseudomonas aeruginosa isolates from cystic fibrosis patients.对来自囊性纤维化患者的铜绿假单胞菌分离株进行基因组指纹分析与传统分型方法的比较。
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Source of Pseudomonas cepacia: ribotyping of isolates from patients and from the environment.洋葱伯克霍尔德菌的来源:患者及环境分离株的核糖体分型
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Epidemic of Pseudomonas cepacia in an adult cystic fibrosis unit: evidence of person-to-person transmission.成人囊性纤维化病房洋葱伯克霍尔德菌感染流行:人传人证据
J Clin Microbiol. 1993 Nov;31(11):3017-22. doi: 10.1128/jcm.31.11.3017-3022.1993.
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