García-Alvarez F, Laclériga A F, Bueno A L, Castiella T, Seral F
Departments of Orthopaedics and Pathology, Hospital Clínico Lozano Blesa Zaragoza, Spain.
Chir Organi Mov. 1999 Apr-Jun;84(2):179-82.
Nora's tumor, also known as bizarre paraosteal osteochondromatous proliferation, is an exophytic outgrowth from the cortical surface that consists of a mixture of bone, cartilage, and fibrous tissue. It is a benign lesion with atypical microscopic features and a tendency to recur. Nora reported 35 cases emerging from the bones of the hands and feet. The largest published series is of 65 cases, with 17 lesions involving the long bones. With this exception, most authors report isolated cases. Age range from 8 to 74 years but most patients are between 20 and 35 years of age, and with the lesion affecting males and females in equal proportions. Usually the presenting symptoMs are due to bony mass, with a variable growth rate (months-years), and infrequent pain. In 15-20% of the cases there was trauma in the patient history: nevertheless, Fechner and Mills report no association with trauma. Radiography shows a calcified, rounded mass emerging directly from the surface of the bone. Isotope bone scans show intense tracer uptake in the lesion. With time, the appearance progresses to the more characteristic mature bone architecture.
诺拉氏肿瘤，也称为奇异的骨旁骨软骨瘤性增殖，是一种从皮质表面向外生长的肿物，由骨、软骨和纤维组织混合组成。它是一种具有非典型微观特征且有复发倾向的良性病变。诺拉报告了35例起源于手足骨骼的病例。已发表的最大病例系列为65例，其中17处病变累及长骨。除此之外，大多数作者报告的都是孤立病例。年龄范围为8至74岁，但大多数患者年龄在20至35岁之间，且该病变在男性和女性中的发生率相等。通常出现的症状是由于骨肿块引起的，生长速度不一（数月至数年），疼痛不常见。在15%至20%的病例中，患者有外伤史：然而，费克纳和米尔斯报告称与外伤无关。X线摄影显示一个钙化的圆形肿块直接从骨表面长出。同位素骨扫描显示病变部位有强烈的示踪剂摄取。随着时间推移，其表现会发展为更具特征性的成熟骨结构。
