Sheludchenko V M, Kurenkov V V, Tamilina E Iu, Shadenkov D A
Vestn Oftalmol. 2001 Jul-Aug;117(4):11-3.
A total of 6682 intrastromal photokeratoablations (LASIK) for myopia of 1.5-16 diopters and hypermetropia of 1.5-8 diopters are analyzed. Lamellar incision of the cornea was formed with a Hansatome microkeratotome and photokeratoablation was carried out using a Nidek EC-5000 laser. Primary and secondary deformations of a corneal flap and primary and secondary adaptation are defined. During LASIK for correction of myopia, the areas of corneal flap and corneal bed can fail to correspond to each other. This non-correspondence is the greater, the deeper is keratoablation. The corneal flap undergoes several stages of changes during the early and remote postoperative periods: primary deformation during lamellar incision, primary dysadaptation presenting as various forms of corneal dystrophy, and secondary deformation developing under new adaptation conditions. The velocity of the corneal flap adaptation depends on its reposition during the final stage of the operation, which can essentially decrease the risk of complications. The incidence of central dystrophy (pseudodiffuse lamellar keratitis) in various methods of the flap reposition varies from 0 to 1.5%.
分析了总共6682例基质内光角膜切除术（准分子激光原位角膜磨镶术，LASIK），这些手术用于矫正1.5至16屈光度的近视以及1.5至8屈光度的远视。使用汉斯刀微型角膜刀制作角膜板层切口，并使用尼德克EC - 5000激光进行光角膜切除术。定义了角膜瓣的原发性和继发性变形以及原发性和继发性适应性。在LASIK矫正近视过程中，角膜瓣和角膜床的面积可能无法相互对应。角膜切削越深，这种不对应就越明显。在术后早期和远期，角膜瓣会经历几个变化阶段：板层切口时的原发性变形、表现为各种形式角膜营养不良的原发性适应不良，以及在新的适应条件下发展的继发性变形。角膜瓣适应的速度取决于手术最后阶段的复位情况，这可显著降低并发症风险。不同角膜瓣复位方法中中央营养不良（假性弥漫性板层角膜炎）的发生率在0至1.5%之间。
