Levanova L A, Aleshkin V A, Vorob'ev A A, Afanas'ev S S, Surikova E V, Rubal'skiĭ O V, Aleshkin A V
State Medical Institute, Kemerovo, Russia.
Zh Mikrobiol Epidemiol Immunobiol. 2001 Jul-Aug(4):47-50.
In 525 young children the state of intestinal microbiocenosis was studied every month of the first year their life. The study revealed that the process of the microflora formation lasted throughout the first year of their life and was characterized by dysbiotic disturbances. During this period the aggravation of dysbiotic changes in the intestine of these children on months 3, 6-7 and 11-12 was of particular importance. The formation of stable dysbacteriosis led to a decrease in the immunological status of the child, which was manifested by the increased content of such microorganisms as hemolytic cocci, Proteus and a decrease in the quantitative level of bifidobacteria in the total intestinal microbiocenosis by the end of the first year of child's life.
对525名幼儿在其生命的第一年每月进行肠道微生物群落状态研究。研究发现,微生物群形成过程在其生命的第一年持续存在,并以生态失调紊乱为特征。在此期间,这些儿童在3个月、6 - 7个月和11 - 12个月时肠道生态失调变化的加剧尤为重要。稳定的菌群失调的形成导致儿童免疫状态下降,表现为溶血球菌、变形杆菌等微生物含量增加,以及在儿童生命第一年结束时,双歧杆菌在肠道微生物群落总量中的定量水平下降。