一名患有支气管源性癌的老年女性因服用佐匹克隆过量致死。

Fatal overdose of zopiclone in an elderly woman with bronchogenic carcinoma.

作者信息

Bramness J G, Arnestad M, Karinen R, Hilberg T

机构信息

National Institute of Forensic Toxicology, Oslo, Norway.

出版信息

J Forensic Sci. 2001 Sep;46(5):1247-9.

PMID:11569575

Abstract

The death of a 72-year-old woman with respiratory debilitation due to bronchogenic carcinoma is described. She overdosed herself with probably 200 to 350 mg of zopiclone. Zopiclone, quantitated by HPLC in femoral postmortem blood, was found to be 1.9 mg/L (4.8 micromol/L). This level is higher than many other zopiclone fatalities reported. We report a case where only zopiclone was detected.

摘要

本文描述了一名72岁因支气管源性癌导致呼吸功能衰弱的女性死亡病例。她过量服用了约200至350毫克佐匹克隆。通过高效液相色谱法对股动脉死后血液中的佐匹克隆进行定量分析，发现其含量为1.9毫克/升（4.8微摩尔/升）。该水平高于许多其他报道的佐匹克隆致死案例。我们报告了一例仅检测出佐匹克隆的病例。