Flocks R H, O'Donoghue E P, Milleman L A, Culp D A
Cancer. 1975 Aug;36(2):705-17. doi: 10.1002/1097-0142(197508)36:2+<705::aid-cncr2820360815>3.0.co;2-#.
Seven surgical treatments for the management of prostatic cancer are briefly reviewed. A transurethral prostatic resection is of value, not only for the relief of bladder outlet obstruction, but also in the definitive management of Stage A lesions. The long-term survival for patients with Stage C disease treated by radical prostatectomy plus interstitial irradiation demonstrates the efficacy of this mode of therapy. Pelvic lymphadenectomy has yielded valuable information on the stage of the disease; long-term survival was related to the presence of lymph node metastases. Lymphadenectomy may have contributed to the 5-year survival rate of those with regional lymph node involvement, but there is no direct evidence to support this view. The early results in patients treated by cryosurgery indicate that this mode of therapy can be very effective in the ablation of the local lesion and may very well have a useful place in the surgical armamentarium for the management of prostatic cancer.
本文简要回顾了七种用于治疗前列腺癌的外科手术方法。经尿道前列腺切除术不仅对缓解膀胱出口梗阻有价值，而且在A期病变的确定性治疗中也有价值。接受根治性前列腺切除术加间质内照射治疗的C期疾病患者的长期生存率证明了这种治疗方式的有效性。盆腔淋巴结清扫术为疾病分期提供了有价值的信息；长期生存与淋巴结转移的存在有关。淋巴结清扫术可能对那些有区域淋巴结受累患者的5年生存率有贡献，但尚无直接证据支持这一观点。冷冻手术治疗患者的早期结果表明，这种治疗方式在局部病灶消融方面可能非常有效，并且很可能在前列腺癌治疗的外科手段中占有一席之地。
