Suit H D, Russell W O
Cancer. 1975 Aug;36(2):759-64. doi: 10.1002/1097-0142(197508)36:2+<759::aid-cncr2820360821>3.0.co;2-u.
Recent advances in radiation therapy in the clinical management of patients with sarcoma of soft tissue are discussed. Radical dose radiation therapy combined with limited surgery has been shown to be highly effective as treatment of early to moderately advanced sarcomas of the extremities. Desmoid tumors which are nonresectable have been treated with moderate to high radiation doses with regular success. The multimodality treatment of rhadbomysarcoma of childhood has yielded a dramatic improvement in 2-year survival figures. This approach includes radiation therapy, multidrug and multicycle chemotherapy, and surgery. Finally, the dominant importance of the histologic grade of sarcoma to the prognosis is discussed in terms of a proposed clinical staging system.
本文讨论了软组织肉瘤患者临床管理中放射治疗的最新进展。根治性剂量放射治疗联合有限手术已被证明是治疗早期至中度晚期肢体肉瘤的高效方法。不可切除的硬纤维瘤采用中高剂量放射治疗通常取得成功。儿童横纹肌肉瘤的多模式治疗使2年生存率有了显著提高。这种方法包括放射治疗、多药多周期化疗和手术。最后，根据提出的临床分期系统，讨论了肉瘤组织学分级对预后的重要影响。
