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用于肉瘤组织保留管理的高剂量局部照射技术。

Techniques to deliver high dose localized irradiation for tissue-sparing management of sarcomas.

作者信息

Kumar P P, Good R R, Jones E O

机构信息

Faculty of the Division of Radiation Oncology, Department of Radiology, University of Nebraska College of Medicine, Omaha 68105.

出版信息

Radiat Med. 1988 Jul-Aug;6(4):171-8.

PMID:3145535
Abstract

Soft tissue sarcomas may be effectively treated conservatively with limited surgery combined with high dose tumor-bed irradiation instead of more radical surgery or amputation alone. High dose local irradiation is safely accomplished with intraoperative electron beam therapy (EBT) or perioperative interstitial 192iridium endocurietherapy (ECT), following external beam radiation therapy (EXRT), to deliver a minimum tumor bed dose of 8,000 rad to 10,000 rad. We describe our techniques for EBT and ECT in the management of soft tissue sarcomas. Two case reports of sarcoma of the pterygoid region treated with EXRT, surgery, and perioperative ECT, and sarcoma of the thigh treated with EXRT, surgery, and intraoperative EBT are used to illustrate the techniques.

摘要

软组织肉瘤可以通过有限手术联合高剂量瘤床放疗进行有效保守治疗,而非单纯采用更激进的手术或截肢。在体外放射治疗(EXRT)后,术中电子束治疗(EBT)或围手术期组织间192铱近距离放疗(ECT)可安全地实现高剂量局部照射,以向瘤床输送至少8000拉德至10000拉德的剂量。我们描述了在软组织肉瘤治疗中EBT和ECT的技术。两个病例报告用于说明这些技术,一个是翼状区域肉瘤接受EXRT、手术和围手术期ECT治疗,另一个是大腿肉瘤接受EXRT、手术和术中EBT治疗。

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