埃及伊蚊脂磷蛋白

Aedes aegypti lipophorin.

作者信息

Capurro M de L, de Bianchi A G, Marinotti O

机构信息

Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, CP, Brazil.

出版信息

Comp Biochem Physiol Biochem Mol Biol. 1994 May;108(1):35-9. doi: 10.1016/0305-0491(94)90161-9.

DOI:10.1016/0305-0491(94)90161-9

PMID:11570397

Abstract

The purified lipophorin of Aedes aegypti (Diptera) is composed of two apolipoproteins: apolipophorin I (M(r)=224,000) and apolipophorin II (M(r)=73,000). The density of lipophorin is constant during the Aedes life-cycle and equal to 1.11 +/- 0.01 g/ml. The amount of lipophorin per animal, during the gonotrophic cycles, increases until 48 hr after blood-feeding and then decreases until there is a new blood intake. The density values and quantification of lipophorin during Aedes aegypti gonotrophic cycle suggest that the adaptation to a higher lipid transport demand during oogenesis in Aedes aegypti is accomplished by increasing the amount of lipophorin in the hemolymph. This response is different from that observed in Musca domestica (Diptera) that does not involve changes in hemolymph lipophorin levels.

摘要

埃及伊蚊（双翅目）纯化的脂磷蛋白由两种载脂蛋白组成：载脂蛋白I（M(r)=224,000）和载脂蛋白II（M(r)=73,000）。在埃及伊蚊的生命周期中，脂磷蛋白的密度恒定，等于1.11±0.01 g/ml。在生殖营养周期中，每只动物的脂磷蛋白量在吸血后48小时内增加，然后减少，直到再次吸血。埃及伊蚊生殖营养周期中脂磷蛋白的密度值和定量表明，埃及伊蚊在卵子发生过程中对更高脂质运输需求的适应是通过增加血淋巴中脂磷蛋白的量来实现的。这种反应与家蝇（双翅目）中观察到的不同，家蝇不涉及血淋巴脂磷蛋白水平的变化。