Kowalske K, Holavanahalli R, Helm P
Department of Physical Medicine and Rehabilitation, University of Texas Southwestern Medical Center at Dallas, 75390-9055, USA.
J Burn Care Rehabil. 2001 Sep-Oct;22(5):353-7; discussion 352. doi: 10.1097/00004630-200109000-00013.
The purpose of this study was to evaluate the incidence of neuropathy in a consecutive cohort of patients with major burn injuries and investigate the clinical correlates for both mononeuropathy and generalized peripheral polyneuropathy. Of 572 patients examined, 64 (11%) patients had clinical evidence of mononeuropathy or peripheral neuropathy or both. Associations of mononeuropathy and peripheral neuropathy with potential risk factors were identified using logistic regression analyses. Electrical cause (odds ratio [OR] = 4.1022, P < .01), history of alcohol abuse (OR = 2.2893, P <.05), and number of days in intensive care (OR = 1.0457, P < .001) were significantly associated with mononeuropathy. The number of days in intensive care (OR = 1.0740, P < .001) and patient age (OR = 1.0543, P < .01) were significantly associated with peripheral neuropathy. This study demonstrates that neuropathy is a common complication of severe burn injury in patients who are older, critically ill, have an electrical cause, or history of alcohol abuse.
本研究的目的是评估一大组严重烧伤患者中神经病变的发生率，并调查单神经病和全身性周围多发性神经病的临床相关因素。在接受检查的572例患者中，64例（11%）有单神经病或周围神经病或两者的临床证据。使用逻辑回归分析确定单神经病和周围神经病与潜在危险因素之间的关联。电击伤（比值比[OR]=4.1022，P<.01）、酗酒史（OR=2.2893，P<.05）和重症监护天数（OR=1.0457，P<.001）与单神经病显著相关。重症监护天数（OR=1.0740，P<.001）和患者年龄（OR=1.0543，P<.01）与周围神经病显著相关。本研究表明，神经病变是老年、重症、有电击伤或酗酒史的严重烧伤患者的常见并发症。
