Tu Yiji, Lineaweaver William C, Zheng Xianyou, Chen Zenggan, Mullins Fred, Zhang Feng
Department of Orthopedic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Joseph M. Still Burn and Reconstruction Center, Jackson, MS, USA.
Burns. 2017 Jun;43(4):693-699. doi: 10.1016/j.burns.2016.08.003. Epub 2017 Mar 24.
Peripheral neuropathy is the most frequent disabling neuromuscular complication of burns. However, the insidious and progressive onset of burn neuropathy makes it often undiagnosed or overlooked. In our study, we reviewed the current studies on the burn-related peripheral neuropathy to summarize the morbidity, mechanism, detecting method and management of peripheral neuropathy in burn patients. Of the 1533 burn patients included in our study, 98 cases (6.39%) were presented with peripheral neuropathy. Thermal and electrical burns were the most common etiologies. Surgical procedures, especially nerve decompression, showed good effect on functional recovery of both acute and delayed peripheral neuropathy in burn patients. It is noteworthy that, for early detection and prevention of peripheral neuropathy, electrodiagnostic examinations should be performed on burn patients independent of symptoms. Still, the underlying mechanisms of burn-related peripheral neuropathy remain to be clarified.
周围神经病变是烧伤最常见的致残性神经肌肉并发症。然而，烧伤神经病变隐匿且呈进行性发展，常导致其未被诊断或被忽视。在我们的研究中，我们回顾了当前关于烧伤相关周围神经病变的研究，以总结烧伤患者周围神经病变的发病率、机制、检测方法及治疗。在我们纳入研究的1533例烧伤患者中，98例（6.39%）出现周围神经病变。热烧伤和电烧伤是最常见的病因。手术治疗，尤其是神经减压术，对烧伤患者急性和迟发性周围神经病变的功能恢复显示出良好效果。值得注意的是，为早期检测和预防周围神经病变，应在烧伤患者中独立于症状进行电诊断检查。尽管如此，烧伤相关周围神经病变的潜在机制仍有待阐明。
