Harder A, Greif G, Haberkorn A
Animal Health Business Group, Research and Development, Biological and Chemical Evaluation, Leverkusen, Germany.
Parasitol Res. 2001 Sep;87(9):785-6. doi: 10.1007/s004360100405.
The situation regarding the treatment of human Giardia and Trichomonas infections and the intestinal and tissue stages of Entamoeba histolytica with metronidazole and other 5-nitroimidazoles is currently satisfactory (Table 1; Mehlhorn 2000). Following correct and rapid diagnosis, the parasites are eliminated reliably and completely. The situation in cases of infection with Acanthamoeba (often involving the eyes) or with Naegleria (often involving the brain) is serious, however. In both cases, there is no drug of choice available. Treatment consists of relieving the symptoms and/or preventing local degeneration.
目前，使用甲硝唑和其他5-硝基咪唑类药物治疗人体贾第虫和滴虫感染以及溶组织内阿米巴的肠道和组织阶段感染的情况令人满意（表1；Mehlhorn，2000年）。经过正确、快速的诊断后，寄生虫能够被可靠且彻底地清除。然而，棘阿米巴感染（通常累及眼睛）或耐格里阿米巴感染（通常累及大脑）的情况则较为严重。在这两种情况下，都没有可供选择的特效药物。治疗主要是缓解症状和/或防止局部组织变性。
