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高危患者和八旬老人腹主动脉瘤的腔内移植物修复术:它比开放修复术更好吗?

Endoluminal graft repair for abdominal aortic aneurysms in high-risk patients and octogenarians: is it better than open repair?

作者信息

Sicard G A, Rubin B G, Sanchez L A, Keller C A, Flye M W, Picus D, Hovsepian D, Choi E T, Geraghty P J, Thompson R W

机构信息

Department of Surgery, Section of Vascular Surgery, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, MO 63110-1093, USA.

出版信息

Ann Surg. 2001 Oct;234(4):427-35; discussion 435-7. doi: 10.1097/00000658-200110000-00002.

Abstract

OBJECTIVE

To analyze the short-term and midterm results of open and endoluminal repair of abdominal aortic aneurysms (AAA) in a large single-center series and specifically in octogenarians.

METHODS

Between January 1997 and October 2000, 470 consecutive patients underwent elective repair of AAA. Conventional open repair (COR) was performed in 210 patients and endoluminal graft (ELG) repair in 260 patients. Ninety of the patients were 80 years of age or older; of these, 38 underwent COR and 52 ELG repair.

RESULTS

Patient characteristics and risk factors were similar for both the entire series and the subgroup of patients 80 years or older. The overall complication rate was reduced by 70% or more in the ELG versus the COR groups. The postoperative death rate was similar for the COR and ELG groups in the entire series and lower (but not significantly) in the ELG 80 years or older subgroup versus the COR group. The 36-month rates of freedom from endoleaks, surgical conversion, and secondary intervention were 81%, 98.2%, and 88%, respectively.

CONCLUSION

The short-term and midterm results of AAA repair by COR or ELG are similar. The death rate associated with this new technique is low and comparable, whereas the complication rate associated with COR in all patients and those 80 years or older in particular is greater and more serious than ELG repair. Long-term results will establish the role of ELG repair of AAA, especially in elderly and high-risk patients.

摘要

目的

在一个大型单中心系列研究中,尤其是针对八旬老人,分析腹主动脉瘤(AAA)开放修复术和腔内修复术的短期及中期结果。

方法

1997年1月至2000年10月期间,470例连续患者接受了AAA择期修复术。210例患者接受了传统开放修复术(COR),260例患者接受了腔内移植物(ELG)修复术。其中90例患者年龄在80岁及以上;在这些患者中,38例行COR,52例行ELG修复术。

结果

整个系列以及80岁及以上患者亚组的患者特征和危险因素相似。与COR组相比,ELG组的总体并发症发生率降低了70%或更多。整个系列中COR组和ELG组的术后死亡率相似,而在80岁及以上的ELG亚组中与COR组相比死亡率较低(但无显著差异)。无内漏、手术转换和二次干预的36个月发生率分别为81%、98.2%和88%。

结论

COR或ELG修复AAA的短期和中期结果相似。与这项新技术相关的死亡率较低且相当,而与COR相关的并发症发生率在所有患者中,尤其是80岁及以上患者中,比ELG修复术更高且更严重。长期结果将确定ELG修复AAA的作用,尤其是在老年和高危患者中。

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