Siergiejko Z, Michno T, Tomorowicz A
Klinika Alergologii i Chorób Wewnetrznych Akademii Medycznej w Białymstoku.
Pneumonol Alergol Pol. 2001;69(3-4):185-92.
Inhalation of hypertonic saline aerosol is a noninvasive method of obtaining sputum for examination of inflammatory processes in the airways. The aim of our investigation was to evaluate the effect of the bronchial provocation test with Dermatophagoides pteronyssinus on both total and differential cell counts in the sputum of allergic asthma patients. The studies were carried out on 20 mild or moderate allergic asthmatics. In each case the studies were performed on three consecutive days. Sputum was induced on the first day of the study, the next day the bronchial provocation test with the allergen was performed and on the last day the sputum induction was repeated again. Twenty-four hours after the allergen challenge an increase in the total cell count and in eosinophils and a decrease in the percentage of macrophages were found in the induced sputum. The above changes were more marked in the patients demonstrating the dual asthmatic reaction after allergen challenge.
吸入高渗盐气雾剂是一种获取痰液以检查气道炎症过程的非侵入性方法。我们研究的目的是评估用尘螨变应原进行支气管激发试验对过敏性哮喘患者痰液中总细胞计数和分类细胞计数的影响。研究针对20名轻度或中度过敏性哮喘患者进行。在每种情况下，研究均连续进行三天。在研究的第一天诱导痰液，第二天进行变应原支气管激发试验，最后一天再次重复痰液诱导。变应原激发后24小时，诱导痰液中总细胞计数、嗜酸性粒细胞增加，巨噬细胞百分比降低。上述变化在变应原激发后出现双重哮喘反应的患者中更为明显。
