Solenov E I, Baturina G S, Ivanova L N
Institute of Cytology and Genetics, Russian Acad. Sci., Siberian Branch, Russia, 630090, Novosibirsk, Pr. Lavrentyeva, 10.
Ross Fiziol Zh Im I M Sechenova. 2001 Jul;87(7):965-72.
Desmopressin caused a statistically significant increase in the water permeability of the outer medullary collecting ducts (OMCD) in 22-days old rats. Concentration of specific V2 receptors increased during postnatal period. Comparison of the V2 receptors concentration, mRNA contents, and changes of water permeability in response to desmopressin suggests that parts of transduction mechanism is situated deeper than the receptors, determines the physiological mechanism at the end of weaning period.
去氨加压素使22日龄大鼠的外髓集合管（OMCD）水通透性出现具有统计学意义的增加。出生后特定V2受体的浓度增加。对V2受体浓度、mRNA含量以及去氨加压素作用下水通透性变化的比较表明，部分转导机制位于比受体更深的位置，决定了断奶期末的生理机制。
