Maly B, Maly A
Department of Pathology, Jerusalem Hadassah University Hospital, Israel.
Acta Cytol. 2001 Sep-Oct;45(5):794-6. doi: 10.1159/000328308.
Nodular fasciitis is a rare benign pseudosarcomatous proliferation of fibroblasts in the breast, in which the clinical examination and mammographic findings may closely mimic mammary carcinoma.
A case of nodular fasciitis was diagnosed by fine needle aspiration. A 15-year-old girl was admitted to our hospital with a recently noticed, rapidly growing mass in the right breast. The aspirate contained cohesive groups of fusiform cells with elongated and oval nuclei, regular nuclear membranes and inconspicuous nucleoli, intermingled with scattered lymphocytes, red blood cells and characteristic granular background substance. A cytologic diagnosis of nodular fasciitis was made and confirmed histologically.
Mammary nodular fasciitis is often clinically suspicious for carcinoma and rarely diagnosed by fine needle aspiration cytology. A literature search yielded only five reported cases. The cytologic diagnosis of this entity helps to choose the correct surgical procedure, preventing psychological trauma to the patient.
结节性筋膜炎是一种罕见的乳腺成纤维细胞良性假肉瘤样增生,其临床检查和乳腺钼靶表现可能与乳腺癌极为相似。
通过细针穿刺确诊一例结节性筋膜炎。一名15岁女孩因近期发现右乳有一迅速生长的肿块入院。穿刺物中含有成簇的梭形细胞,细胞核呈细长形和椭圆形,核膜规则,核仁不明显,其间夹杂散在的淋巴细胞、红细胞和特征性颗粒状背景物质。作出结节性筋膜炎的细胞学诊断,并经组织学证实。
乳腺结节性筋膜炎在临床上常疑似为癌,很少通过细针穿刺细胞学诊断。文献检索仅发现5例报道病例。该病变的细胞学诊断有助于选择正确的手术方式,避免给患者造成心理创伤。