Chen S P, Sung P J, Duh C Y, Dai C F, Sheu J H
Department of Marine Resources, National Sun Yat-Sen University, Kaohsiung 804, Taiwan, Republic of China.
J Nat Prod. 2001 Sep;64(9):1241-2. doi: 10.1021/np010192r.
A new sesquiterpenoid, junceol A(1), as well as two known diterpenoids, sclerophytin A (2) and cladiellisin (3), have been isolated from the sea pen octocoral Virgularia juncea. The structure of metabolite 1 was determined by extensive spectral analysis. Compounds 1-3 have been shown to exhibit cytotoxicity toward P-388 cancer cells.
从海笔八放珊瑚琼氏拟角珊瑚（Virgularia juncea）中分离出一种新的倍半萜类化合物琼氏醇A（1），以及两种已知的二萜类化合物硬叶素A（2）和克拉迪菌素（3）。代谢物1的结构通过广泛的光谱分析确定。已证明化合物1-3对P-388癌细胞具有细胞毒性。
