Fleischhack G, Simon A
Zentrum für Kinderheilkunde des Universitätsklinikums BonnAbteilung Pädiatrische Hämatologie/Onkologie, Bonn, Germany.
Klin Padiatr. 2001 Sep;213 Suppl 1:A5-8. doi: 10.1055/s-2001-17498.
The control of severe infectious complications by preventive strategies, early diagnosis of infections and empiric broad-spectrum antibiotic therapy contributed to a marked improvement of survival in children with cancer over the last 20 years. This article overviews of the importance of prevention of infectious complications in immunocompromised pediatric patients with hematologic or oncologic diseases. The particular challenge of this age group with respect to the acquisition and the spread of pathogens, the spectrum of causative microorganisms and the principal issues of anti-infectious prophylaxis are considered.
在过去20年中，通过预防策略、感染的早期诊断和经验性广谱抗生素治疗来控制严重感染并发症，使得癌症患儿的生存率显著提高。本文概述了预防血液学或肿瘤性疾病免疫受损儿科患者感染并发症的重要性。文中考虑了该年龄组在病原体获得和传播、致病微生物谱以及抗感染预防的主要问题方面所面临的特殊挑战。
