Abdou Nabih I
University of Missouri School of Medicine and St. Luke's Hospital, Kansas City, Missouri, USA.
Clin Allergy Immunol. 2002;16:435-47.
Progress has been made in the classification, characterization, and identification of vasculitis; a heterogeneous disease with various vessel sizes and types of involvement. Understanding pathogenetic mechanisms and the kinetics of the inflammatory-immune response is still in its infancy. With the availability of new tools for diagnosis and the use of molecular biological techniques at the cellular, tissue, and fluid phase levels will open the doors for new understanding of the etiology and mechanism(s) of this group of diseases.
在血管炎的分类、特征描述及诊断方面已取得进展;血管炎是一种累及不同血管大小和类型的异质性疾病。对其发病机制及炎症免疫反应动力学的认识仍处于起步阶段。随着新的诊断工具的出现以及分子生物学技术在细胞、组织和液相水平的应用,将为深入了解这类疾病的病因及发病机制打开大门。