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从白喉棒状杆菌PW8中分离出一株治愈菌株。

Isolation of a cured strain from Corynebacterium diphtheriae PW8.

作者信息

Ishii-Kanei C, Uchida T, Yoneda M

出版信息

Infect Immun. 1979 Sep;25(3):1081-3. doi: 10.1128/iai.25.3.1081-1083.1979.

Abstract

A nonlysogenic, non-toxinogenic strain was isolated from the PW8 strain of C. diphtheriae by two-step ultraviolet induction. This strain was lysed by phages derived from the PW8 strain but not by beta phages from the C7(beta) strain. When this cured strain was lysogenized with phages from the PW8 strain, toxin production by the resulting lysogens was about a half or a quarter of that of the parent strain PW8.

摘要

通过两步紫外线诱导从白喉棒状杆菌PW8菌株中分离出一种非溶原性、无毒菌株。该菌株可被源自PW8菌株的噬菌体裂解,但不能被C7(β)菌株的β噬菌体裂解。当用来自PW8菌株的噬菌体使该治愈菌株溶原化时,所得溶原菌产生的毒素约为亲本菌株PW8的一半或四分之一。

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