必奇液对大鼠胃黏膜的保护作用。
Protective effect of Pepto-Bismol liquid on the gastric mucosa of rats.
作者信息
Goldenberg M M, Honkomp L J, Burrous S E, Castellion A W
出版信息
Gastroenterology. 1975 Sep;69(3):636-40.
Pepto-Bismol liquid (primary active constituent, bismuth subsalicy-late) protected the gastric mucosa of rats against the formation of hemorrhagic lesions or erosions in response to cold + restraint stress, to a combination of aspirin and cold + restraint stress, and to ethyl alcohol. The protective effect of Pepto-Bismol in these studies was clearly demonstrated. Although the mechanism of action of Pepto-Bismol was not delineated, there was a suggestion that the degree of coating of the gastric mucosa was related to protection.
必奇口服液（主要活性成分碱式水杨酸铋）可保护大鼠胃黏膜，使其免受因寒冷加束缚应激、阿司匹林与寒冷加束缚应激联合作用以及乙醇所致的出血性病变或糜烂的影响。必奇在这些研究中的保护作用得到了明确证实。尽管必奇的作用机制尚未明确，但有迹象表明胃黏膜的覆盖程度与保护作用有关。
Zotero 插件