Eph receptors tingle the spine.
作者信息
Henkemeyer M, Frisén J
机构信息
Center for Developmental Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
出版信息
Neuron. 2001 Sep 27;31(6):876-7. doi: 10.1016/s0896-6273(01)00441-x.
Abstract
During the development of excitatory synapses, molecules cluster on dendrites to form postsynaptic densities, and specialized structures known as spines appear. EphB2 is demonstrated to control this process by associating with and phosphorylating a key postsynaptic molecule, syndecan-2, thereby initiating the maturation of dendritic spines.
摘要
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