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肾上腺偶发瘤的临床及组织病理学评估

Clinical and histopathological evaluation of the adrenal incidentaloma.

作者信息

Sworczak K, Babńiska A, Stanek A, Lewczuk A, Siekierska-Hellmann M, Błaut K, Drobińska A, Basiński A, Lachński A J, Czaplińska-Kałas H, Gruca Z

机构信息

Department of Internal Medicine, Endocrinology and Hemostatic Disorders, Medical University of Gdańsk, Poland.

出版信息

Neoplasma. 2001;48(3):221-6.

Abstract

Clinically silent adrenal masses (incidentaloma) are incidentally discovered lesions, when noninvasive imaging methods (USG, CT, MRI) are performed for reasons other than known or suspected adrenal disease. Most studies report on a prevalence of adrenal incidentaloma range between 1% and 10% in radiological series. Between 1994 and 1999 we observed in our Department 57 patients with incidentalomas of adrenal glands. After endocrinological evaluation silent Cushing's syndrome was found in 2 cases (3.5%). Fifty two patients were qualified for surgery. Adrenocortical adenoma was diagnosed in 73.1%; adrenocortical carcinoma in 7.7%; pheochromocytoma in 7.7% and less frequent adrenal lesions in 11.5%. All adrenal carcinomas and malignant pheochromocytomas (11.5%) were found in tumors with diameter over 4 cm.

摘要

临床无症状肾上腺肿块(偶发瘤)是在因已知或疑似肾上腺疾病以外的原因进行非侵入性成像检查(超声、CT、MRI)时偶然发现的病变。大多数研究报告显示,放射学检查系列中肾上腺偶发瘤的患病率在1%至10%之间。1994年至1999年期间,我们科室观察到57例肾上腺偶发瘤患者。经内分泌评估,2例(3.5%)发现为无症状库欣综合征。52例患者符合手术条件。诊断为肾上腺皮质腺瘤的占73.1%;肾上腺皮质癌占7.7%;嗜铬细胞瘤占7.7%,其他少见肾上腺病变占11.5%。所有肾上腺皮质癌和恶性嗜铬细胞瘤(11.5%)均见于直径超过4 cm的肿瘤。

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