Babińska Anna, Sworczak Krzysztof, Siekierska-Hellmann Małgorzata, Lewczuk Anna, Błaut Krzysztof, Obołoiczyk Lukasz, Wiśniewski Piotr, Zielonko Joanna, Kaska Lukasz, Lachiński Andrzej
Kliniki Chorób Wewnetrznych, Endokrynologii i Zaburzeń Hemostazy, Akademii Medycznej w Gdańsku.
Wiad Lek. 2006;59(11-12):744-50.
Clinically silent adrenal masses (incidentaloma) are incidentally discovered lesions when noninvasive imaging methods (ultrasonography--USG, computer tomography--CT, magnetic resonance imaging--MRI) are performed for the reason other than known or suspected adrenal disease. Most of studies report the prevalence of adrenal incidentaloma range between 1 and 10% in radiological series.
Between 1993 and 03.2004 we observed 198 patients with incidentalomas of adrenal glands (144 females--72.7% and 54 males--27.3%).
After endocrinological evaluation, 164 patients were qualified for surgery. In 119 (72.5%) cases open adrenalectomy was performed, and in 45 (27.5%) laparoscopic adrenalectomy was done. Adrenocortical adenoma was diagnosed in 54.9%, adrenal hyperplasia in 8.5%, adrenal carcinoma in 6.7%, pheochromocytoma in 12.9% (in 3.1% of all cases malignant pheochromocytoma was diagnosed), in 4.9% others malignant tumors (primary or metastatic), in 4.9% adrenal cysts and in 7.1% other rare adrenal pathologies were found.
All malignancies were found in tumors with the diameter over 3 cm. In tumors with diameter over 6 cm malignant cases were found in 70.8%.
临床无症状肾上腺肿块(偶发瘤)是在因已知或疑似肾上腺疾病以外的原因进行非侵入性成像检查(超声检查——USG、计算机断层扫描——CT、磁共振成像——MRI)时偶然发现的病变。大多数研究报告在放射学系列中肾上腺偶发瘤的患病率在1%至10%之间。
1993年至2004年3月期间,我们观察了198例肾上腺偶发瘤患者(144例女性——72.7%,54例男性——27.3%)。
经过内分泌评估,164例患者符合手术条件。119例(72.5%)行开放性肾上腺切除术,45例(27.5%)行腹腔镜肾上腺切除术。诊断为肾上腺皮质腺瘤的占54.9%,肾上腺增生的占8.5%,肾上腺癌的占6.7%,嗜铬细胞瘤的占12.9%(所有病例中3.1%诊断为恶性嗜铬细胞瘤),4.9%为其他恶性肿瘤(原发性或转移性),4.9%为肾上腺囊肿,7.1%为其他罕见的肾上腺病变。
所有恶性肿瘤均在直径超过3 cm的肿瘤中发现。直径超过6 cm的肿瘤中恶性病例占70.8%。