Pickart C M
Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA.
Mol Cell. 2001 Sep;8(3):499-504. doi: 10.1016/s1097-2765(01)00347-1.
The latest advances in ubiquitin-mediated signaling were discussed at a recent FASEB meeting in Vermont. New findings show that besides signaling proteolysis, ubiquitination can be a signal for trafficking, kinase activation, and other nonproteolytic fates.
在佛蒙特州最近举行的一次美国实验生物学会联合会会议上,讨论了泛素介导信号传导的最新进展。新的研究结果表明,除了作为蛋白水解的信号外,泛素化还可以作为运输、激酶激活及其他非蛋白水解命运的信号。