Hixson M J, Collins J H
J Reprod Med. 2001 Sep;46(9):849-52.
Herpes simplex virus (HSV) can cause postpartum endometritis. The clinical diagnosis of HSV endometritis has been reported previously. The disease is responsive to acyclovir intravenously.
A 22-year-old woman, gravida 2, para 1, status post primary cesarean section for a double footling breech presentation, developed a persistent postpartum fever. Simulating the febrile course of septic pelvic thrombophlebitis, the patient's condition was unresponsive to broad-spectrum antimicrobials and heparin therapy. Active herpetic lesions and a positive cervical culture for herpes simplex prompted the use of intravenous acyclovir. Rapid resolution of the fever and the similarity to previous case reports suggested the clinical diagnosis of herpes simplex endometritis.
The diagnosis of postpartum herpes simplex endometritis should be considered when managing a persistent postpartum fever unresponsive to aggressive antimicrobial and heparin therapy. Immediate resolution of the fever should occur with the use of acyclovir.
单纯疱疹病毒(HSV)可引起产后子宫内膜炎。此前已有关于HSV子宫内膜炎临床诊断的报道。该疾病对静脉注射阿昔洛韦有反应。
一名22岁女性,孕2产1,因双足先露行初次剖宫产术后,出现持续性产后发热。模拟感染性盆腔血栓性静脉炎的发热病程,患者的病情对广谱抗菌药物和肝素治疗无反应。活跃的疱疹病变以及单纯疱疹宫颈培养阳性促使使用静脉注射阿昔洛韦。发热迅速消退且与既往病例报告相似提示单纯疱疹子宫内膜炎的临床诊断。
在处理对积极抗菌和肝素治疗无反应的持续性产后发热时,应考虑产后单纯疱疹子宫内膜炎的诊断。使用阿昔洛韦应能使发热立即消退。