Szinnai G, Schaad U B, Heininger U
University Children's Hospital (UKBB), Basel, Switzerland.
Eur J Pediatr. 2001 Sep;160(9):528-33. doi: 10.1007/s004310100800.
Herpetic whitlow is a herpes simplex virus type 1 or 2 infection of the fingers characterised by erythema and painful, non-purulent vesicles. In children it typically occurs after auto-inoculation from herpes stomatitis, herpes labialis or genitalis. Occasionally, person-to-person transmission occurs from family members with herpes labialis. We report a 4-year-old girl with multiple herpetic whitlows secondary to herpetic stomatitis and present a review of the medical literature based on a systematic MEDLINE search of published paediatric patients (English, French and German language). Of 42 identified patients, 72% were younger than 2 years, most had endogenous or exogenous inoculation of herpes simplex virus type 1 and 65% were initially misdiagnosed as having "bacterial felon". Recurrences were reported in 23%.
herpetic whitlow should be suspected based on clinical signs. Specific diagnosis can be made by polymerase chain reaction or culture. The high rate of misdiagnosed cases indicates that this entity is not sufficiently known. Lesions are self-limited; surgical interventions can be harmful and should be avoided. Recurrences occur as frequently as in adults.
疱疹性瘭疽是由1型或2型单纯疱疹病毒引起的手指感染,其特征为红斑和疼痛性非脓性水疱。在儿童中,它通常在因疱疹性口炎、唇疱疹或生殖器疱疹进行自体接种后发生。偶尔,会通过患有唇疱疹的家庭成员发生人际传播。我们报告了一名4岁女童,继发于疱疹性口炎出现多处疱疹性瘭疽,并基于对已发表的儿科患者(英语、法语和德语)进行的MEDLINE系统检索,对医学文献进行综述。在42例已识别患者中,72%年龄小于2岁,大多数患者为1型单纯疱疹病毒的内源性或外源性接种,65%最初被误诊为“细菌性甲沟炎”。23%的患者有复发报告。
应根据临床体征怀疑疱疹性瘭疽。可通过聚合酶链反应或培养进行特异性诊断。误诊率高表明该疾病未得到充分认识。病变具有自限性;手术干预可能有害且应避免。复发情况与成人一样常见。